The fibrolamellar variant of hepatocellular carcinoma. Its association with focal nodular hyperplasia
نویسندگان
چکیده
منابع مشابه
CT-Value (△HU and CT-Value ratioin) differential diagnosis of small hepatocellular carcinoma from focal nodular hyperplasia
Background: The objective was to explore the value of the CT value difference (△HU) and CT value ratio (CVR) between the hepatic arterial (AP), portal (PP), and delayed phases (DP) to differentiate the small Hepatocellular Carcinoma (SHCC, ≤ 3 cm) from the small Focal nodular hyperplasia (SFNH, ≤ 3 cm). Materials and Methods: All the lesions were confirmed by clinically and/or pathologically an...
متن کاملFocal nodular hyperplasia with concomitant hepatocellular carcinoma: a case report and clonal analysis.
This report describes a hepatocellular carcinoma (HCC) with concomitant focal nodular hyperplasia (FNH) in a 56 year old Chinese man. There were two well circumscribed tumours measuring 3 x 2.5 x 2 cm and 2 x 1.5 x 1.5 cm. The larger mass was grey and soft with a small area of bleeding and necrosis and an intact capsule. The smaller mass was yellow and had no capsule. Clonal analysis was carrie...
متن کاملMolecular pathogenesis of focal nodular hyperplasia and hepatocellular adenoma.
Focal nodular hyperplasia (FNH) and hepatocellular adenomas (HCAs) are benign tumors that occur in otherwise normal liver parenchyma. FNH is considered to be the result of a hyperplastic response to increased blood flow secondary to vascular malformations. Most FNH are polyclonal and to date, the molecular pathway and mechanisms that are altered in FNH have yet to be elucidated. In contrast, HC...
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The Fibrolamellar variant of Hepatocellular Carcinoma (FLHCC) is a rare form of liver cancer that presents in the 3rd decade of life, is rarely associated with cirrhosis or chronic Hepatitis B/C virus infection, and usually presents with normal serum alpha-fetoprotein (AFP) levels. FLHCC presenting during pregnancy is extremely rare, with only 4 cases reported. We present a case of FLHCC in pre...
متن کاملCold agglutinin disease in fibrolamellar hepatocellular carcinoma: a rare association with a rare cancer variant
Cold agglutinin disease (CAD) is a rare autoimmune hemolytic anemia. Although it can occur secondary to lymphoproliferative disorders and autoimmune or infectious diseases, CAD is rarely reported as secondary to solid tumors. We report a case of a woman aged 18 years diagnosed with a well-differentiated hepatocellular carcinoma of the fibrolamellar subtype, who was shown to have CAD also. Her g...
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ژورنال
عنوان ژورنال: Cancer
سال: 1987
ISSN: 0008-543X,1097-0142
DOI: 10.1002/1097-0142(19871215)60:12<3049::aid-cncr2820601232>3.0.co;2-m